Scientific References

AUTHORS : Alepee N. Bessou S. Boullay E. De Smedt A De Wever B Gregoire S. Jones P A Kunkel A. McNamee P Millet M. Pfannenbecker U Taalman R. Tailhardat M. Van Goethem F Wargniez W.

MODELS : HCE / HUMAN CORNEAL EPITHELIUM

APPLICATIONS : OCULAR IRRITATION OF CHEMICAL

In vitro Eye Irritation RhT Test Methods for Dyes. COLIPA Program on Optimization and Validation of HPLC Bio-Analytical Assay to Expand Applicability Domain of in vitro Eye Irritation RhT Test Methods for Dyes.

2012 SOT Society of Toxicology annual meeting | L'Oréal Research & Innovation, Pierre Fabre, Janssen Research & Development, Henkel AG & Co. KGaA, Unilever, Beiersdorf, The Procter & Gamble Company, COLIPA, LVMH Recherche

AUTHORS : Antignac E. Clouzeau J. Persaud R. Re Thomas Srinivasan V.

MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS

APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL PHARMACOLOGY / TOXICOLOGY PHOTOPROTECTION Phototoxicity SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN SENSITIZATION SYSTEMIC TOXICITY

Safety Assessment of Botanicals: A Decision Tree Approach for the Safety Assessment of Botanical Cosmetic Ingredients

2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation

AUTHORS : Alepee N. Amsellem Carole Bertino Beatrice Bremond Christelle Capallere Christophe Cotovio J de Brugerolle de Fraissinette A. Grandidier MH Leclaire J Lee AV Lelièvre D Loisel-Joubert Sophie Maloug Saber Meunier Jean-Roch Minondo Anne-Marie Ovigne Jean-Marc Tinois-Tessonneaud Estelle

MODELS : HCE / HUMAN CORNEAL EPITHELIUM

APPLICATIONS : Eye irritation OCULAR IRRITATION OF CHEMICAL

In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic HCE model: application to 435 substances from consumer products industry.

2010 Toxicology In Vitro. 2010 Mar;24(2):523-37. | L'Oréal, Research & Innovation

AUTHORS : Adriaens E. Alepee N. Cappadoro M Catoire S De Wever B Hansen E Straube F Van Goethem F Vanparys P Wolf A

MODELS : HCE / HUMAN CORNEAL EPITHELIUM

APPLICATIONS : OCULAR IRRITATION OF CHEMICAL

Prevalidation of a new in vitro reconstituted human cornea model to assess the eye irritating potential of chemicals

2006 Toxicol In Vitro. 2006 Feb;20(1):1-17. Epub 2005 Jul 12. | Johnson & Johnson Pharmaceutical Research and Development, Turnhoutseweg 30, B-2340 Beerse, Belgium. [email protected]

AUTHORS : Botham Philip A

MODELS : EPISKIN

APPLICATIONS : OCULAR IRRITATION OF CHEMICAL Skin corrosion SKIN IRRITATION OF CHEMICALS

ECVAM, ECETOC and the EU Chemicals Policy. Alternatives to animal experiments: Progress made and challenges ahead. The proceedings of the ECVAM Status Seminar 2002, held on 4-6 June 2002, in the amphitheatre at the European Commission Joint Research Centr

2002 ATLA Alternatives to laboratory animals 2002 ;30 (SUP2):185-187 | Syngenta Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, SK10 4TJ, United Kingdom

AUTHORS : Liebsch M Spielmann H

APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL Phototoxicity Skin corrosion SKIN IRRITATION OF CHEMICALS

Currently available in vitro methods used in the regulatory toxicology

2002 Toxicol Lett 2002 Feb 28 ;127 (1-3):127-34 | National Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET), Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV), Diedersdorfer Weg 1, D-12277 Berlin, Germany. [email protected]

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